Investigating the origins of pelvic recurrence in colorectal cancer
IRAS Number: 136843
CPMS ID: 17065
ClinicalTrials.gov ID: NCT02292641
Trial Start Date: Sept-14
Recruitment End Date: Dec-26
Trial End date: Dec-31
We are trying to find out where, why and how patients get recurrent bowel cancer in their pelvis. We also want to find out which treatments can help. In this study we are introducing a new format for reporting MRIs which provides more detailed information about the recurrence which will improve management of your recurrence and therefore outcome. We will also compare this new structured report with the original scans of the original tumour which will help us understand how this recurrence happened. We hope that by understanding how these recurrences occur we can prevent them from occurring in the future.
A prospective and retrospective cohort study, Beyond TME Origins aims to improve surgical and treatment planning using an imaging assessment proforma of advanced and recurrent colorectal cancers. This involves the implementation of imaging assessment proformas describing anatomic pelvic compartments and aetiology of disease recurrence for treatment planning.
All patients with recurrent colorectal cancer in the pelvis are eligible. The original primary tumour staging scans and resected surgical specimen needs to be available. Patients’ recurrence will be staged using our proposed MRI classification. We will be assessing the original primary staging scans and histopathology to learn about risk factors for recurrence. We will record treatment for the recurrence, and patients will be followed up for three years.
The Beyond TME trial is open to new sites.
Please fill in the form below if you would like further information or have any questions about any aspect of the trial.
